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Daniel L Alkon Selected Research

8- (2- (2- pentyl- cyclopropylmethyl)cyclopropyl)octanoic acid

1/2011PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice.

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Daniel L Alkon Research Topics

Disease

29Alzheimer Disease (Alzheimer's Disease)
01/2022 - 02/2002
9Dementia (Dementias)
01/2019 - 04/2004
5Amyloid Plaque
01/2022 - 01/2011
5Ischemic Stroke
10/2015 - 08/2009
5Memory Disorders (Memory Loss)
06/2015 - 02/2007
5Cognitive Dysfunction
08/2006 - 05/2002
4Stroke (Strokes)
01/2017 - 09/2008
3Intellectual Disability (Idiocy)
10/2020 - 02/2002
3Brain Ischemia (Cerebral Ischemia)
12/2013 - 01/2012
3Insulin Resistance
05/2008 - 07/2006
2Fragile X Syndrome (Martin Bell Syndrome)
10/2020 - 06/2014
2Neurodegenerative Diseases (Neurodegenerative Disease)
05/2015 - 05/2003
2Disease Progression
05/2009 - 08/2006
2Neoplasms (Cancer)
07/2004 - 02/2003
1Autism Spectrum Disorder
10/2020
1Nervous System Diseases (Neurological Disorders)
01/2017
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
10/2015
1Thrombosis (Thrombus)
12/2013
1Necrosis
12/2013
1Traumatic Brain Injuries (Traumatic Brain Injury)
12/2013
1Atrophy
12/2013
1Infarction (Infarctions)
12/2013
1Ischemia
12/2013
1Gliosis
12/2013
1Brain Injuries (Brain Injury)
12/2013
1Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain)
08/2009
1Mood Disorders (Mood Disorder)
06/2008
1Inflammation (Inflammations)
10/2007
1Experimental Diabetes Mellitus
11/2005
1AIDS-Related Complex (ARC)
10/2005
1Neuroblastoma
08/2005
1Type 2 Diabetes Mellitus (MODY)
04/2004
1Neoplasm Metastasis (Metastasis)
02/2003
1Hypoxia (Hypoxemia)
02/2002

Drug/Important Bio-Agent (IBA)

10Protein Kinase CIBA
06/2015 - 04/2008
9BryostatinsIBA
01/2022 - 11/2005
8Biomarkers (Surrogate Marker)IBA
01/2015 - 08/2006
8IsoenzymesIBA
01/2012 - 10/2005
7Amyloid (Amyloid Fibrils)IBA
01/2018 - 02/2005
7Proteins (Proteins, Gene)FDA Link
05/2009 - 05/2003
5Pharmaceutical PreparationsIBA
10/2020 - 07/2004
5Amyloid beta-PeptidesIBA
01/2019 - 05/2002
5Protein Isoforms (Isoforms)IBA
01/2015 - 10/2005
4bryostatin 1IBA
01/2017 - 07/2004
4Peptides (Polypeptides)IBA
01/2014 - 02/2005
4Insulin (Novolin)FDA Link
05/2008 - 11/2005
3EnzymesIBA
10/2006 - 05/2003
2Therapeutic UsesIBA
01/2019 - 07/2004
2Protein Kinase C-epsilonIBA
01/2018 - 01/2017
2Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2018 - 06/2015
2Apolipoprotein E4IBA
01/2017 - 05/2015
2Fragile X Mental Retardation ProteinIBA
05/2016 - 06/2014
2Tissue Plasminogen Activator (Alteplase)FDA Link
10/2015 - 12/2013
2Amyloidogenic ProteinsIBA
01/2011 - 10/2002
2Insulin ReceptorIBA
05/2008 - 04/2004
2Phosphotransferases (Kinase)IBA
10/2007 - 12/2003
2Insulysin (Insulin-Degrading Enzyme)IBA
10/2006 - 07/2006
2Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
12/2003 - 10/2002
2Cholinergic Agents (Cholinergics)IBA
05/2002 - 02/2002
18- (2- (2- pentyl- cyclopropylmethyl)cyclopropyl)octanoic acidIBA
01/2011
1Glycogen Synthase Kinase 3 betaIBA
05/2009
1tau Proteins (tau Protein)IBA
05/2009
1CholesterolIBA
06/2008
1Ro 31-8220IBA
12/2007
1Glycogen Synthase (Synthase I)IBA
10/2007
1C-Reactive ProteinIBA
10/2007
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2006
1BradykininIBA
08/2006
1Interleukin-6 (Interleukin 6)IBA
08/2006
1CytokinesIBA
08/2006
1Gonadal Steroid Hormones (Sex Hormones)IBA
02/2006
1LactonesIBA
11/2005
1MacrolidesIBA
11/2005
1Streptozocin (Streptozotocin)FDA Link
11/2005
1Messenger RNA (mRNA)IBA
10/2005
1Phorbol EstersIBA
08/2005
1MitogensIBA
12/2003
1Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
12/2003
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
12/2003
1AntioxidantsIBA
05/2003
1Extracellular Matrix ProteinsIBA
02/2003
1Annexin A2 (Annexin II)IBA
02/2003
1PlasminogenIBA
02/2003
1Peptide Hydrolases (Proteases)FDA Link
02/2003
1Mitogen-Activated Protein KinasesIBA
10/2002
1Carbonic Anhydrases (Carbonic Anhydrase)IBA
02/2002
1Adenosine (Adenocard)FDA LinkGeneric
02/2002

Therapy/Procedure

6Therapeutics
06/2015 - 06/2006
1Intraperitoneal Injections
11/2005